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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169508Generated: October 30, 2026

2-(1-(3,4-Dichlorophenyl)cyclopentyl)acetonitrile → 2-(1-(3,4-Dichlorophenyl)-cyclopentyl)-acetamidine hydrochloride

https://huagongshe.com/reaction/2169508

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-(3,4-Dichlorophenyl)cyclopentyl)acetonitrileHCID 86726128—
Reactant2-[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochlorideHCID 86726131—
Product2-(1-(3,4-Dichlorophenyl)-cyclopentyl)-acetamidine hydrochlorideHCID 86726129—

Reaction Steps

2-(1-(3,4-Dichlorophenyl)-cyclopentyl)-acetamidine hydrochloride (486) was synthesized from 2-(1-(3,4-dichlorophenyl)cyclopentyl)acetonitrile (485) following the procedure described for the HCl-salt of 2-[1-(4-trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochloride (242).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-e45719bf690844fc83f1dab0daf28b87
Source noteuspto-grants-2015_06