[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetonitrile → 2-(1-(3-Chlorophenyl)cyclopentyl)acetonitrile

HRID 2169519Notes

Reaction equation

HRID 2169519 reaction equation
CS(O[CH2:6][C:7]1([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[CH:13]=2)[CH2:11][CH2:10][CH2:9][CH2:8]1)(=O)=O.FC(F)(F)C1C=CC(C2(C[C:33]#[N:34])CCCC2)=CC=1>>[Cl:18][C:14]1[CH:13]=[C:12]([C:7]2([CH2:6][C:33]#[N:34])[CH2:11][CH2:10][CH2:9][CH2:8]2)[CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 86725930[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetonitrileHCID 86726139(1-(3-Chlorophenyl)cyclopentyl)methyl methanesulfonate

Product 1

HCID 867261402-(1-(3-Chlorophenyl)cyclopentyl)acetonitrile

Procedure

2-(1-(3-Chlorophenyl)cyclopentyl)acetonitrile (498) was synthesized from (1-(3-chlorophenyl)cyclopentyl)methyl methanesulfonate (497) following the procedure described for [1-(4-trifluoromethyl-phenyl)-cyclopentyl]-acetonitrile (241).

Sources & evidence

ORD record
ord-1964091ce7684c9ebe75264d3a436e0b
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Reaction notes

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