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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169519Generated: November 1, 2026

[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetonitrile → 2-(1-(3-Chlorophenyl)cyclopentyl)acetonitrile

https://huagongshe.com/reaction/2169519

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetonitrileHCID 86725930—
Reactant(1-(3-Chlorophenyl)cyclopentyl)methyl methanesulfonateHCID 86726139—
Product2-(1-(3-Chlorophenyl)cyclopentyl)acetonitrileHCID 86726140—

Reaction Steps

2-(1-(3-Chlorophenyl)cyclopentyl)acetonitrile (498) was synthesized from (1-(3-chlorophenyl)cyclopentyl)methyl methanesulfonate (497) following the procedure described for [1-(4-trifluoromethyl-phenyl)-cyclopentyl]-acetonitrile (241).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-1964091ce7684c9ebe75264d3a436e0b
Source noteuspto-grants-2015_06