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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169521Generated: October 30, 2026

2-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochloride → HCID 178450809, compound

https://huagongshe.com/reaction/2169521

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochlorideHCID 86726141—
ReactantHCID 178450810HCID 178450810—
ProductHCID 178450809HCID 178450809—

Reaction Steps

tert-butyl 5-(benzyloxy)-2-((1-(3-chlorophenyl)cyclopentyl)methyl)-6-hydroxypyrimidine-4-carboxylate (500) was synthesized as a white solid from 2-(1-(3-chlorophenyl)-cyclopentyl)-acetamidine hydrochloride (499) following the procedure described for 5-benzyloxy-2-[1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl]-6-hydroxypyrimidine-4-carboxylic acid tert-butyl ester (243).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-4ac76826633a445f940cead8c28fc70d
Source noteuspto-grants-2015_06