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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169887Generated: October 27, 2026

2-Amino-6-fluorobenzonitrile → N-(1-(3-amino-2-cyanophenoxy)-2-methylpropan-2-yl)cyclohexanecarboxamide

https://huagongshe.com/reaction/2169887

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-fluorobenzonitrileHCID 522659—
ReactantN-(1-hydroxy-2-methylpropan-2-yl)cyclohexanecarboxamideHCID 39240152—
ProductN-(1-(3-amino-2-cyanophenoxy)-2-methylpropan-2-yl)cyclohexanecarboxamideHCID 66745570—

Reaction Steps

Prepared as in Example 22b from N-(1-hydroxy-2-methylpropan-2-yl)cyclohexanecarboxamide (Example 37c) and 2-amino-6-fluorobenzonitrile as an off-white solid (29%). MS 316 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09049878B2
Source datasetuspto-grants-2015_06
ORD IDord-980e3b4ea24a435c8d6578666677808f
Source noteuspto-grants-2015_06