HRID2170015

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID244

Benzyl alcohol

C7H8O

HCID3672

Ibuprofen

C13H18O2

3 次

HCID3423265

Sodium Lauryl Sulfate

C12H25NaO4S

结构：O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.[Sr+2]

HCID140483007

未命名化合物

PRODUCTS

生成物

结构：CC(C)Cc1ccc(C(C)C(=O)O)cc1.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.[Sr+2]

HCID178440861

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

Strontium ascorbate (900 mg) from Example 8 and sodium lauryl sulphate (450 mg) were mixed into Ibux gel 5% (produced by Weifa AS, Oslo, Norway) using a mortar and pestle. (Ibux gel contains 5% ibuprofen in a hydrogel comprising hydroxyethylcellulose, benzylalcohol, isopropanol, sodium hydroxyl and purified water). The resulting gel contained 1.2% wt strontium.

WORKUP

后处理

custompurified water)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-45996a62a26144f194bb2d119e9f8841
来源数据集: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09050312B2
来源说明: uspto-grants-2015_06

反应 SMILES

[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([O-:6])=[C:3]1[OH:4].[Sr+2:13].[O:14]=[C:15]1[O:21][C@H:20]([C@H:22]([CH2:24][OH:25])[OH:23])[C:18]([O-:19])=[C:16]1[OH:17].S([O-])(OCCCCCCCCCCCC)(=O)=O.[Na+].[CH3:44][CH:45]([CH2:47][C:48]1[CH:53]=[CH:52][C:51]([CH:54]([C:56]([OH:58])=[O:57])[CH3:55])=[CH:50][CH:49]=1)[CH3:46].C(O)C1C=CC=CC=1>C(O)(C)C>[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([O-:6])=[C:3]1[OH:4].[Sr+2:13].[OH:58][C:56]([CH:54]([C:51]1[CH:50]=[CH:49][C:48]([CH2:47][CH:45]([CH3:44])[CH3:46])=[CH:53][CH:52]=1)[CH3:55])=[O:57].[O:14]=[C:15]1[O:21][C@H:20]([C@H:22]([CH2:24][OH:25])[OH:23])[C:18]([O-:19])=[C:16]1[OH:17]