Hydrochloric Acid → N-(6-(1-amino-2-(3,5-difluorophenyl)ethyl)-5-bromopyridin-2-yl)acetamide hydrochloride

Participants

Reaction Steps

(S)—N-(5-Bromo-6-(2-(3,5-difluorophenyl)-1-(1,1-dimethylethylsulfinamido)ethyl)pyridin-2-yl)acetamide (1E, crude material from last step) was treated with a mixture of 2 ml of 1.25 M HCl in MeOH (methanol)/1 ml of 4 M HCl in dioxane for 1 hour. The solvent was removed in vacuo. The crude material was used without further purification. MS (m/z) 369.9 [M+H]+.

Provenance & Evidence