HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-(1-benzyl-7-methoxy-3,4-dihydro-1H-naphthalen-2-ylidene)-pyrrolidinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 1-(7-Methoxy-3,4-dihydro-naphthalen-2-yl)-pyrrolidine | HCID 12264684 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-(1-benzyl-7-methoxy-3,4-dihydro-1H-naphthalen-2-ylidene)-pyrrolidinium bromide | HCID 71008563 | — |
Reaction Steps
To a mixture of 1-(7-methoxy-3,4-dihydro-naphthalen-2-yl)-pyrrolidine (320 g, 1.4 mol) in MeCN (1000 mL) was added BnBr (263 g, 1.54 mol) dropwise at room temperature and stirred for 1 h. Then the solvent was evaporated in vacuo to give crude 1-(1-benzyl-7-methoxy-3,4-dihydro-1H-naphthalen-2-ylidene)-pyrrolidinium bromide which was directly used for next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051280B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-e3aa4f91dcf643548614d1b618b9f92f |
| Source note | uspto-grants-2015_06 |