2-Bromoethyl methyl ether → HCID 67169435, compound

HRID 2170851Notes

Reaction equation

HRID 2170851 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]([O:12][CH3:13])=[O:11])[CH:8]=2)[CH:3]=[CH:2]1.Br[CH2:15][CH2:16][O:17][CH3:18]>>[CH3:18][O:17][CH2:16][CH2:15][N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]([O:12][CH3:13])=[O:11])[CH:8]=2)[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 639844Methyl indole-6-carboxylate

Product 1

HCID 67169435HCID 67169435, compoundYield 30%

Procedure

The title compound was prepared in 30% yield (79 mg, colorless syrup) from methyl 1H-indole-6-carboxylate (200 mg, 1.14 mmol) and 1-bromo-2-methoxyethane (190 mg, 1.37 mmol) by the similar manner in Step-1 of Intermediate-9.

Sources & evidence

ORD record
ord-561afd8c184448e4bcbbe2b2fd6f07df
Source dataset
uspto-grants-2015_06
Patent number
US09051296B2

Reaction notes

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