O-Methylhydroxylamine hydrochloride → HCID 86654645, compound

HRID 2170879Notes

Reaction equation

HRID 2170879 reaction equation
[CH3:1][C:2]1[C:3]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[N:4][N:5]([C:7]2[N:28]=[CH:27][CH:26]=[CH:25][C:8]=2[C:9]([NH:11][CH:12]([CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:13]([OH:17])[C:14](O)=[O:15])=[O:10])[CH:6]=1.Cl.[CH3:36][O:37][NH2:38]>>[OH:17][CH:13]([C:14]([NH:38][O:37][CH3:36])=[O:15])[CH:12]([NH:11][C:9](=[O:10])[C:8]1[CH:25]=[CH:26][CH:27]=[N:28][C:7]=1[N:5]1[CH:6]=[C:2]([CH3:1])[C:3]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)=[N:4]1)[CH2:18][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 521874O-Methylhydroxylamine hydrochlorideHCID 67239656HCID 67239656, compound

Product 1

HCID 86654645HCID 86654645, compound

Procedure

The reaction was carried out in analogy to reaction step 1.3 by reacting 3-(2-(4-methyl-3-phenyl-1H-pyrazol-1-yl)nicotinamido)-2-hydroxy-4-phenylbutanoic acid with O-methylhydroxylamine hydrochloride. ESI-MS [M+H]+: 486.2

Workup

  1. customThe reaction was carried out in analogy to reaction step 1.3

Sources & evidence

ORD record
ord-17cfccf1483e4871b11afa112854d055
Source dataset
uspto-grants-2015_06
Patent number
US09051304B2

Reaction notes

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