O-Methylhydroxylamine hydrochloride → HCID 86654650, compound

HRID 2170885Notes

Reaction equation

HRID 2170885 reaction equation
[OH:1][CH:2]([CH:6]([NH:16][C:17](=[O:35])[C:18]1[CH:23]=[CH:22][CH:21]=[N:20][C:19]=1[N:24]1[CH:28]=[CH:27][C:26]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[N:25]1)[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1)[C:3]([OH:5])=O.Cl.[CH3:37][O:38][NH2:39]>>[OH:1][CH:2]([C:3]([NH:39][O:38][CH3:37])=[O:5])[CH:6]([NH:16][C:17](=[O:35])[C:18]1[CH:23]=[CH:22][CH:21]=[N:20][C:19]=1[N:24]1[CH:28]=[CH:27][C:26]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)=[N:25]1)[CH2:7][C:8]1[CH:9]=[CH:10][C:11]([O:14][CH3:15])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 521874O-Methylhydroxylamine hydrochlorideHCID 67240639HCID 67240639, compound

Product 1

HCID 86654650HCID 86654650, compound

Procedure

The reaction was carried out in analogy to reaction step 1.3 by reacting 2-hydroxy-4-(4-methoxyphenyl)-3-(2-(3-phenyl-1H-pyrazol-1-yl)nicotinamido)butanoic acid with O-methylhydroxylamine hydrochloride. ESI-MS [M+H]+: 502.2

Workup

  1. customThe reaction was carried out in analogy to reaction step 1.3

Sources & evidence

ORD record
ord-d997816b6aa1444e815aeaf2e06f51d9
Source dataset
uspto-grants-2015_06
Patent number
US09051304B2

Reaction notes

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