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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2170919Generated: October 30, 2026

HCID 86723573, compound → HCID 86723572, compound

https://huagongshe.com/reaction/2170919

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86723573HCID 86723573—
SolventHydrochloric AcidHCID 313—
ProductHCID 86723572HCID 86723572—

Reaction Conditions

Temperature100 °C

Reaction Steps

4-(4-cyclopropyl-1H-imidazol-1-yl)-5-fluoropicolinate (640 mg, 2.11 mmol) was dissolved in 1N HCl (5 mL) and the reaction was heated to 100° C. overnight. The solvent was removed, CH3CN was added and the solvent removed to afford 4-(4-cyclopropyl-1H-imidazol-1-yl)-5-fluoropicolinic acid which was used directly in subsequent reactions (assuming 100% conversion).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051313B2
Source datasetuspto-grants-2015_06
ORD IDord-9eee23859f4d47e68d686b9edebb1d92
Source noteuspto-grants-2015_06