HCID 54049649, compound → 3-Ethyl-4-formylbenzonitrile

HRID 2170952Notes

Reaction equation

HRID 2170952 reaction equation
[CH:1]([C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][C:4]=1[CH:11]=[CH2:12])=[O:2]>C(O)C.[Pd]>[CH2:11]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:3]=1[CH:1]=[O:2])[C:7]#[N:8])[CH3:12]

Participants

4

Reactant 1

HCID 54049649HCID 54049649, compound

Product 1

HCID 178193273-Ethyl-4-formylbenzonitrile

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 1.3 g (8.27 mmol) of 4-formyl-3-vinylbenzonitrile in 35 ml of ethanol is mixed with 880 mg of 10% palladium on carbon and vigorously stirred under a hydrogen atmosphere for 2 h. The suspension is filtered through a layer of kieselguhr, the residue is washed with ethanol, and the filtrate is concentrated. The residue (890 mg) is employed without further purification in the following stage.

Workup

  1. filtrationThe suspension is filtered through a layer of kieselguhr
  2. washthe residue is washed with ethanol
  3. concentrationthe filtrate is concentrated
  4. customThe residue (890 mg) is employed without further purification in the following stage

Sources & evidence

ORD record
ord-6575eeae044e4e2dba095542d25e31e9
Source dataset
uspto-grants-2015_06
Patent number
US09051316B2

Reaction notes

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