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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171345Generated: October 31, 2026

Potassium Carbonate → HCID 135743575, compound

https://huagongshe.com/reaction/2171345

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 86724161HCID 86724161—
SolventWaterHCID 962—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 135743575HCID 135743575—

Reaction Conditions

Temperature70 °C

Reaction Steps

To a mixture of N-(2-bromoethyl)-2,6-dichloropyrimidin-4-amine (10 g, 18 mmol) in 1,4-dioxane (30 mL) and water (30.0 mL) was added K2CO3 (4.85 g, 35.1 mmol). The reaction mixture was stirred at 70° C. for 4 h, then directly used into next step without workup and purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-8562e7c7119a4ae18bd200313ce49d34
Source noteuspto-grants-2015_06