Isopropyl iodide → HCID 86728333, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 7-chloro-2,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one (400 mg, 2.00 mmol) and 2-iodopropane (375 mg, 2.20 mmol) in acetonitrile (7 mL) was added Cs2CO3 (1.31 g, 4.01 mmol). The reaction mixture was stirred at 90° C. for 2 h, filtered and concentrated. Purification via MDAP afforded the title product (40 mg) as a white solid.

Provenance & Evidence