4-(2-Fluoro-4-(hydroxymethyl)phenoxy)-2-(trifluoromethyl)benzonitrile → 4-(4-(((1,2-Dimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)oxy)methyl)-2-fluorophenoxy)-2-(trifluoromethyl)benzonitrile

Participants

Role	Name	HCID	Charge
Reactant	4-(2-Fluoro-4-(hydroxymethyl)phenoxy)-2-(trifluoromethyl)benzonitrile	HCID 71239725	—
Reactant	7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one	HCID 86728314	—
Product	4-(4-(((1,2-Dimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)oxy)methyl)-2-fluorophenoxy)-2-(trifluoromethyl)benzonitrile	HCID 86728338	—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and 4-(2-fluoro-4-(hydroxymethyl)phenoxy)-2-(trifluoromethyl)benzonitrile.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09051325B2
Source dataset	uspto-grants-2015_06
ORD ID	ord-bf6c0295c9ff4f60ac0fca99ada936fe
Source note	uspto-grants-2015_06