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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171381Generated: November 2, 2026

2,4,5-Trifluorobenzyl Alcohol → (S)-1,2-dimethyl-7-((2,4,5-trifluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171381

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,5-Trifluorobenzyl AlcoholHCID 2777035—
Reactant(S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728322—
Product(S)-1,2-dimethyl-7-((2,4,5-trifluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728357—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E1 starting from (S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (2,4,5-trifluorophenyl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-0b28b233fe7647bcad6bebaae64e0fe1
Source noteuspto-grants-2015_06