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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171387Generated: October 25, 2026

(3-Fluoro-4-(3-fluorophenoxy)phenyl)methanol → (S)-7-((3-fluoro-4-(3-fluorophenoxy)benzyl)oxy)-2-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171387

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Fluoro-4-(3-fluorophenoxy)phenyl)methanolHCID 28946122—
Reactant(S)-tert-butyl 7-chloro-2-methyl-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylateHCID 86728347—
Product(S)-7-((3-fluoro-4-(3-fluorophenoxy)benzyl)oxy)-2-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728362—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E9 starting from (3-fluoro-4-(3-fluorophenoxy)phenyl)methanol and (S)-tert-butyl 7-chloro-2-methyl-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-9d877eae13044dd897f52b1ad0254ccb
Source noteuspto-grants-2015_06