HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-((2-Chloropyridin-4-yl)oxy)-3-fluorophenyl)methanol → 7-((4-((2-chloropyridin-4-yl)oxy)-3-fluorobenzyl)oxy)-2,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-((2-Chloropyridin-4-yl)oxy)-3-fluorophenyl)methanol | HCID 86724216 | — |
| Reactant | tert-butyl 7-chloro-2,2-dimethyl-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate | HCID 86728374 | — |
| Product | 7-((4-((2-chloropyridin-4-yl)oxy)-3-fluorobenzyl)oxy)-2,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one | HCID 86728415 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E9 starting from (4-((2-chloropyridin-4-yl)oxy)-3-fluorophenyl)methanol and tert-butyl-7-chloro-2,2-dimethyl-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051325B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-110cbecfa3544371ac575cd34df73444 |
| Source note | uspto-grants-2015_06 |