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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171456Generated: November 1, 2026

2,4,5-Trifluorobenzyl Alcohol → 1,2,2-trimethyl-7-((2,4,5-trifluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171456

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,5-Trifluorobenzyl AlcoholHCID 2777035—
Reactant7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728345—
Product1,2,2-trimethyl-7-((2,4,5-trifluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728441—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (2,4,5-trifluorophenyl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-01eda625d2974088ab3f444a3181ae0f
Source noteuspto-grants-2015_06