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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2172347Generated: October 25, 2026

Formaldehyde → Ethyl 2-(4-bromophenyl)acrylate

https://huagongshe.com/reaction/2172347

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantPotassium CarbonateHCID 11430—
ReactantEthyl 2-(4-bromophenyl)acetateHCID 7020609—
CatalystTetrabutylammonium IodideHCID 67553—
SolventTolueneHCID 1140—
ProductEthyl 2-(4-bromophenyl)acrylateHCID 11470828—

Reaction Steps

is prepared by treating a toluene solution of (4-bromo-phenyl)-acetic acid ethyl ester with paraformaldehyde, potassium carbonate, tetrabutylammonium iodide according to the following literature: H. Stalder, M. Boes Chimia 2000, 54, 669-671.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051448B2
Source datasetuspto-grants-2015_06
ORD IDord-0ce283c2bbad4867ad6caa8597cb1b33
Source noteuspto-grants-2015_06