HCID 68006739, compound → HCID 86667391, compound

HRID 2172407Notes

Reaction equation

HRID 2172407 reaction equation
[NH:1]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19][NH:18][CH2:17][CH2:16][NH:15][CH2:14][CH2:13][NH:12][CH2:11][CH2:10][CH2:9][NH:8][CH2:7][CH2:6][NH:5][CH2:4][CH2:3][CH2:2]1.[F:24][C:25]([OH2+])([F:27])[F:26]>>[F:24][C:25]([F:27])([F:26])[N:1]1[CH2:23][CH2:22][N:21]([C:25]([F:27])([F:26])[F:24])[CH2:20][CH2:19][N:18]([C:25]([F:27])([F:26])[F:24])[CH2:17][CH2:16][N:15]([C:25]([F:27])([F:26])[F:24])[CH2:14][CH2:13][N:12]([C:25]([F:27])([F:26])[F:24])[CH2:11][CH2:10][CH2:9][N:8]([C:25]([F:27])([F:26])[F:24])[CH2:7][CH2:6][N:5]([C:25]([F:27])([F:26])[F:24])[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 68006739HCID 68006739, compoundHCID 86667392HCID 86667392, compound

Product 1

HCID 86667391HCID 86667391, compoundYield 50.2%

Procedure

8 g (0.024 mol) of 1,5,8,12,15,18,21-Heptaazacyclotricosane and 90.9 g (0.168 mol) of the trifluoromethyl oxonium salt were refluxed in an argon atmosphere for 3 hours to produce 9.7 g of 1,5,8,12,15,18,21-Heptakis(trifluoromethyl)-1,5,8,12,15,18,21-heptaazacyclotricosane represented by Formula 12 below.

Sources & evidence

ORD record
ord-c3056fc771f5470393dc391a0c4290c0
Source dataset
uspto-grants-2015_06
Patent number
US09054392B2

Reaction notes

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