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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 217266Generated: October 30, 2026

Methyl 3-[bis(tert-butoxycarbonyl)amino]-5-iodothiophene-2-carboxylate → HCID 59481839, compound

https://huagongshe.com/reaction/217266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-[bis(tert-butoxycarbonyl)amino]-5-iodothiophene-2-carboxylateHCID 45480424—
ReactantHCID 57703583HCID 57703583—
ProductHCID 59481839HCID 59481839—

Reaction Steps

Intermediate VII.5 was prepared starting from methyl 3-(bis[ter-butoxycarbonyl]amino)-5-iodo-2-thiophenecarboxylate and 2-[4(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]furo[3,2-b]pyridine (according to the general procedure in WO 2008/017688) as described for Intermediate VII.1. Intermediate VII.5 was used for the next step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08193372B2
Source datasetuspto-grants-2012_06
ORD IDord-77d926414c9245038e015b2f394a2412
Source noteuspto-grants-2012_06