Hydrogen chloride-ethyl acetate → HCID 86725359, compound

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Reaction Steps

3-[(4-Oxo-5-(3-(2-t-butoxycarbonylaminoethyloxy)benzylidene)-2-thioxothiazolidin-3-yl)amino]-1,2-benzothiazole 1,1-dioxide (220 mg) obtained in Example 167 was dissolved in 4M hydrogen chloride-ethyl acetate solution (10 ml), and the solution was stirred at room temperature for 3 hr, and concentrated under reduced pressure to give 3-[(4-oxo-5-(3-(2-aminoethyloxy)benzylidene)-2-thioxothiazolidin-3-yl)amino]-1,2-benzothiazole 1,1-dioxide hydrochloride (167 mg).

Provenance & Evidence