HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86672757, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 72213060 | HCID 72213060 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86672757 | HCID 86672757 | — |
Reaction Steps
To a stirred solution of [1-(2-bromo-pyridin-4-yl)-cyclopropyl]-carbamic acid tert-butyl ester (0.160 g, 0.511 mmol) in dichloromethane (3 mL) is added trifluoroacetic acid (1.0 mL, 13 mmol) at room temperature. After 18 hours, the reaction mixture is concentrated in vacuo to yield crude title compound (ES+ m/z 213.49, 215.40) as an oil, which is used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09056858B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-5d56619915164a42bad3c17135173e67 |
| Source note | uspto-grants-2015_06 |