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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2172967Generated: October 30, 2026

Trifluoroacetic acid → HCID 86672757, compound

https://huagongshe.com/reaction/2172967

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 72213060HCID 72213060—
SolventDichloromethaneHCID 6344—
ProductHCID 86672757HCID 86672757—

Reaction Steps

To a stirred solution of [1-(2-bromo-pyridin-4-yl)-cyclopropyl]-carbamic acid tert-butyl ester (0.160 g, 0.511 mmol) in dichloromethane (3 mL) is added trifluoroacetic acid (1.0 mL, 13 mmol) at room temperature. After 18 hours, the reaction mixture is concentrated in vacuo to yield crude title compound (ES+ m/z 213.49, 215.40) as an oil, which is used without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056858B2
Source datasetuspto-grants-2015_06
ORD IDord-5d56619915164a42bad3c17135173e67
Source noteuspto-grants-2015_06