反应详情

[1-(5-Methanesulfonyl-furan-2-yl)-cyclopropyl]-carbamic acid tert-butyl ester (0.430 g, 1.42 mmol) is dissolved in a 4M solution of HCl in dioxane (5.0 mL, 20 mmol) at room temperature. After stirring for 16 hours, the mixture is evaporated under a stream of nitrogen. The resulting oily solid is suspended in ethyl acetate (5 mL), ethyl ether (25 mL) is added, and the mixture is filtered to afford crude title product as a solid, which is used without purification.

1. customthe mixture is evaporated under a stream of nitrogen
2. additionethyl ether (25 mL) is added
3. filtrationthe mixture is filtered