4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochloride → HCID 67517283, compound

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Reaction Steps

6-Iodo-5-[2-(piperazin-1-yl)ethyl]-2-benzofuran-1(3H)-one hydrochloride was prepared from tert-butyl-4-[2-(6-iodo-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazine-1-carboxylate using 4N HCl in dioxane in an analogous fashion to that described for the synthesis of 4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochloride above. LC-MS (IE, m/z): 373 [M+1]+.

Provenance & Evidence