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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173132Generated: November 1, 2026

4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochloride → HCID 67515896, compound

https://huagongshe.com/reaction/2173132

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochlorideHCID 67517229—
ReactantHCID 86692999HCID 86692999—
ProductHCID 67515896HCID 67515896—

Reaction Steps

4-Cyclopropyl-5-[2-(piperazin-1-yl)ethyl]-2-benzofuran-1(3H)-one was prepared in a similar fashion to that described for the synthesis of 4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochloride above starting from tert-butyl-4-[2-(4-cyclopropyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazine-1-carboxylate. LC-MS (IE, m/z): 275 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056859B2
Source datasetuspto-grants-2015_06
ORD IDord-10c65b4d92134237befa3617eda1b8ee
Source noteuspto-grants-2015_06