HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl (1-oxo-1,3-dihydro-2-benzofuran-5-yl)acetate → (1-Oxo-1,3-dihydro-2-benzofuran-5-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl (1-oxo-1,3-dihydro-2-benzofuran-5-yl)acetate | HCID 77230657 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | (1-Oxo-1,3-dihydro-2-benzofuran-5-yl)acetic acid | HCID 67518033 | — |
Reaction Steps
tert-Butyl (1-oxo-1,3-dihydro-2-benzofuran-5-yl)acetate (1.2 g, 4.8 mmol) was dissolved in TFA and stirred at room temperature for one h. The reaction mixture was concentrated and pumped under vacuum overnight to afford the title compound. LC-MS (IE, m/z): 193.2 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09056859B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-c62a8fe2907d4f8b86e5442bd5f96207 |
| Source note | uspto-grants-2015_06 |