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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173299Generated: October 29, 2026

1,4-Dioxane hydrochloride → HCID 67516969, compound

https://huagongshe.com/reaction/2173299

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ReactantHCID 67517382HCID 67517382—
ProductHCID 67516969HCID 67516969—

Reaction Steps

Compound tert-butyl 4-[(7-cyano-2,3-dihydro-1-benzofuran-3-yl)methyl]piperazine-1-carboxylate (76 mg, 0.22 mmol) was added HCl/dioxane (4 N) and the resulting mixture was stirred at room temperature for 3 hours, and then the solvents were removed under vacuum to give the crude 3-(piperazin-1-ylmethyl)-2,3-dihydro-1-benzofuran-7-carbonitrile hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056859B2
Source datasetuspto-grants-2015_06
ORD IDord-31ba23cfbbcc4fd59c18968fe233b6fc
Source noteuspto-grants-2015_06