Trifluoroacetic acid → HCID 118035801, compound

HRID 2173428Notes

Reaction equation

HRID 2173428 reaction equation
[N:1]1([C:6]2[CH:7]=[C:8]([CH2:12][CH2:13][N:14]3[CH2:19][CH2:18][N:17](C(OC(C)(C)C)=O)[CH2:16][CH2:15]3)[CH:9]=[CH:10][CH:11]=2)[CH:5]=[N:4][N:3]=[N:2]1.[C:27]([OH:33])([C:29]([F:32])([F:31])[F:30])=[O:28]>>[F:30][C:29]([F:32])([F:31])[C:27]([O-:33])=[O:28].[N:1]1([C:6]2[CH:7]=[C:8]([CH2:12][CH2:13][N:14]3[CH2:15][CH2:16][NH2+:17][CH2:18][CH2:19]3)[CH:9]=[CH:10][CH:11]=2)[CH:5]=[N:4][N:3]=[N:2]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 89754182HCID 89754182, compound

Product 1

HCID 118035801HCID 118035801, compound

Procedure

The t-butyl 4-{2-[3-(1H-tetrazol-1yl)phenyl]ethyl}piperazine-1-carboxylate (280 mg, 2.15 mmol) was stirred in TFA (5 ml) for ½ hr then concentrated and dried to yield 4-{2-[3-(1h-tetrazol-1yl)phenyl]ethyl}piperazin-1-ium trifluoroacetate. LC-MS (IE, m/z): 259 [M+1]+.

Workup

  1. concentrationthen concentrated
  2. customdried

Sources & evidence

ORD record
ord-c5e817406bf44437bce0e1a7f15c1328
Source dataset
uspto-grants-2015_06
Patent number
US09056859B2

Reaction notes

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