3-Nitrophenethyl bromide → 1{4-[2-(3-Nitrophenyl)ethyl]piperazin-1-yl}-2-[4-(1H-tetrazol-1-yl)phenyl]ethanone

Participants

Reaction Steps

1-{4-[2-(3-Nitrophenyl)ethyl]piperazin-1-yl}-2-[4-(1H-tetrazol-1-yl)phenyl]ethanone was prepared from 1-(2-bromoethyl)-3-nitrobenzene and 1-(piperazin-1-yl)-2-[4-(1H-tetrazol-1-ylphenyl]ethanone in an analogous fashion to that described for the synthesis of 1-{8-[2-(4-nitrophenyl)ethyl]-3,8-diazabicyclo[3.2.1]oct-3-yl}-2-[4-(1H-tetrazol-1-yl)phenyl]ethanone. LC/MS: [(M+1)]+=422.

Provenance & Evidence