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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173454Generated: October 30, 2026

HCID 67517237, compound → HCID 67517684, compound

https://huagongshe.com/reaction/2173454

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67517237HCID 67517237—
ReactantHCID 77230677HCID 77230677—
SolventEthanolHCID 702—
ProductHCID 67517684HCID 67517684—

Reaction Steps

A solution of 1-(piperazin-1-yl)-2-[4-(1H-tetrazol-1-yl)phenyl]ethanone (200 mg, 0.734 mmol), 6-(oxiran-2-yl)-3,4-dihydro-1H-isochromen-1-one (140 mg, 0.734 mmol) in ethanol was heated in a microwave reactor at 130° C. for 1 h. The reaction mixture was concentrated and the residue was purified by preparative TLC to afford the title compound. LC/MS: [(M+1]+=463.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056859B2
Source datasetuspto-grants-2015_06
ORD IDord-e0ccfd8755d244789003f7b93230291c
Source noteuspto-grants-2015_06