HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67517237, compound → HCID 67517684, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67517237 | HCID 67517237 | — |
| Reactant | HCID 77230677 | HCID 77230677 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67517684 | HCID 67517684 | — |
Reaction Steps
A solution of 1-(piperazin-1-yl)-2-[4-(1H-tetrazol-1-yl)phenyl]ethanone (200 mg, 0.734 mmol), 6-(oxiran-2-yl)-3,4-dihydro-1H-isochromen-1-one (140 mg, 0.734 mmol) in ethanol was heated in a microwave reactor at 130° C. for 1 h. The reaction mixture was concentrated and the residue was purified by preparative TLC to afford the title compound. LC/MS: [(M+1]+=463.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09056859B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-e0ccfd8755d244789003f7b93230291c |
| Source note | uspto-grants-2015_06 |