5-Methoxytetralone → HCID 86703350, compound

HRID 2173678Notes

Reaction equation

HRID 2173678 reaction equation
O[C:2]1[CH:11]=[CH:10][C:9]2[CH2:12][CH2:13][CH2:14][CH2:15][N:7]3[C:8]=2[C:3]=1[C:4](=O)[CH2:5][CH2:6]3.C[O:18]C1C=CC=C2C=1CCCC2=O>>[OH:18][C:10]1[C:9]2[CH2:12][CH2:13][CH2:14][CH2:15][N:7]3[C:8]=2[C:3]([CH2:4][CH2:5][CH2:6]3)=[CH:2][CH:11]=1

Participants

3

Reactant 2

HCID 366205-MethoxytetraloneHCID 86703351HCID 86703351, compound

Product 1

HCID 86703350HCID 86703350, compound

Procedure

The title compound was synthesized in a similar manner as 11-hydroxy-2,3,5,6,7,8-hexahydro-1H-azepino[3,2,1-ij]quinolone starting from 5-methoxytetralone: 1H NMR (DMSO-d6) δ 8.69 (s, 1H), 6.55 (d, 1H); 6.27 (d, 1H), 3.05-3.02 (m, 2H), 2.92-2.89 (m, 2H), 2.68-2.64 (m, 2H), 2.54 (t, 2H), 1.69-1.60 (m, 4H), 1.45-1.37 (m, 2H); MS expected 204 (C13H18NO, M+1), found 204.

Sources & evidence

ORD record
ord-b406d98d69804ac4b21e27930e01312c
Source dataset
uspto-grants-2015_06
Patent number
US09056885B2

Reaction notes

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