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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2173763Generated: October 30, 2026

Tert-butyl 3-bromobutanoate → tert-Butyl 3-[2-(2,6-bis-hydroxymethyl-pyridin-4-yloxy)-ethylamino]-butanoate

https://huagongshe.com/reaction/2173763

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 3-bromobutanoateHCID 57092335—
ReactantN-[2-(2,6-bis-hydroxymethyl-pyridin-4-yloxy)-ethyl]-2-nitro-benzenesulfonamideHCID 66713939—
Producttert-Butyl 3-[2-(2,6-bis-hydroxymethyl-pyridin-4-yloxy)-ethylamino]-butanoateHCID 66716520—

Reaction Steps

Prepared as for Ex. 2, starting with tert-butyl 3-bromo-butyrate and N-[2-(2,6-bis-hydroxymethyl-pyridin-4-yloxy)-ethyl]-2-nitro-benzenesulfonamide:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09056914B2
Source datasetuspto-grants-2015_06
ORD IDord-09db2ba024d141b8af0405ea338b80cd
Source noteuspto-grants-2015_06