Methyl iodide → HCID 86709238, compound

HRID 2174149Notes

Reaction equation

HRID 2174149 reaction equation
[C:1]1([N:7]2[C:11]3[C:12]4[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=4[S:14][C:10]=3[N:9]=[CH:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:19][I:20]>CCOC(C)=O>[I-:20].[CH3:19][N+:9]1[C:10]2[S:14][C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[C:11]=2[N:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH:8]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 86709237HCID 86709237, compound

Product 1

HCID 86709238HCID 86709238, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 1-phenyl-1H-benzo[4,5]thieno[2,3-d]imidazole (4 g, 16 mmol) and methyl iodide (11.36 g, 80 mmol) in EtOAc (100 ml) was stirred for 48 h at room temperature. The precipitate was isolated by filtration and washed thoroughly with EtOAc to yield 3-methyl-1-phenyl-1H-benzo[4,5]thieno[2,3-d]imidazol-3-ium iodide (5.52 g, 88%) as a white solid.

Workup

  1. customThe precipitate was isolated by filtration
  2. washwashed thoroughly with EtOAc

Sources & evidence

ORD record
ord-0620f2bd555e428baad74fed888f14d0
Source dataset
uspto-grants-2015_06
Patent number
US09059412B2

Reaction notes

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