Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | Quinoline, 7,8-Difluoro- | HCID 3025799 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 68285982 | HCID 68285982 | — |
Reaction Steps
185.5 g (1.12 mol) of 7,8-difluoroquinoline, 505.4 g (2.25 mol) of N-iodosuccinimide and 927 mL of acetic acid were placed in a 3 L eggplant flask containing a stirrer, followed by stirring the mixture for 30 hours at 90° C. After cooling the resultant, the precipitated crystals were filtered and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09060517B2 |
|---|
| Source dataset | uspto-grants-2015_06 |
|---|
| ORD ID | ord-433be3a89c8542e3ab1a413ea7718263 |
|---|
| Source note | uspto-grants-2015_06 |
|---|
