HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86712405, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-5-fluoroquinoxaline | HCID 12686404 | — |
| Reactant | HCID 86673628 | HCID 86673628 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86712405 | HCID 86712405 | 26.7% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
0.32 g of 3-(2-fluoro-6-hydroxy-phenyl)-3-methyl-butan-2-one and 0.28 g of 2-chloro-5-fluoro-quinoxaline were dissolved in 3 ml of dimethylformamide. 0.25 g of potassium carbonate were added thereto followed by stirring for 2 hours at 100° C. Subsequently, the reaction mixture was purified by silica gel column chromatography to obtain 0.14 g of 3-[2-fluoro-6-(5-fluoro-quinoxalin-2-yloxy)-phenyl]-3-methyl-butan-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09060517B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-3ec1853e12804aa5833eb4e18af1fbe0 |
| Source note | uspto-grants-2015_06 |