HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86712407, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 86712408 | HCID 86712408 | — |
| Reactant | HCID 86712409 | HCID 86712409 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 86712407 | HCID 86712407 | 89.4% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
0.17 g of 2-chloro-5,6-difluoro-3-methylquinoxaline were dissolved in 2 mL of N-methylpyrrolidone. 0.13 g of 2-(1-methoxy-1-methyl-ethyl)-pyridin-3-ol and 0.11 g of potassium carbonate were added thereto followed by stirring for 3 hours at 100° C. Subsequently, the reaction solution was purified by silica gel column chromatography to obtain 0.24 g of 5,6-difluoro-2-[2-(1-methoxy-1-methyl-ethyl)-pyridin-3-yloxy]-3-methyl-quinoxaline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09060517B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-5eaef84c74074d828f5489e30dd3434c |
| Source note | uspto-grants-2015_06 |