N,N-Dimethylethylenediamine → HCID 53353782, compound

HRID 2174531Notes

Reaction equation

HRID 2174531 reaction equation
[Cl:1][C:2]1[C:3](=[O:19])[N:4]([CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[CH2:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:5]=[CH:6][C:7]=1Cl.[CH3:20][N:21]([CH3:25])[CH2:22][CH2:23][NH2:24]>>[Cl:1][C:2]1[C:3](=[O:19])[N:4]([CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[CH2:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:5]=[CH:6][C:7]=1[NH:24][CH2:23][CH2:22][N:21]([CH3:25])[CH3:20]

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 53353682HCID 53353682, compound

Product 1

HCID 53353782HCID 53353782, compound

Procedure

4-Chloro-5-(2-dimethylaminoethyl)amino-2-(3,3,5,5-tetramethylcyclohexyl)pyridazin-3-one was prepared from 4,5-Dichloro-2-(3,3,5,5-tetramethyl cyclohexyl)pyridazin-3-one in a similar manner using 2-Dimethylaminoethyl amine (4 equivalents). 1H NMR (300 MHz CDCl3) 7.60 (s, 1H), 5.44 (m, 1H), 5.33 (m, 1H), 3.33 (m, 2H), 2.59 (m, 2H), 2.29 (s, 6H), 1.55 (m, 4H), 1.3 (m, 1H), 1.15 (m, 1H), 1.15 (s, 6H), 0.95 (s, 6H).

Sources & evidence

ORD record
ord-38b570f36b564b789f3dffa0397ce50e
Source dataset
uspto-grants-2015_06
Patent number
US09062004B2

Reaction notes

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