N,N-Dimethylethylenediamine → HCID 53353783, compound

HRID 2174532Notes

Reaction equation

HRID 2174532 reaction equation
[Br:1][C:2]1[C:3](=[O:19])[N:4]([CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[CH2:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:5]=[CH:6][C:7]=1Br.[CH3:20][N:21]([CH3:25])[CH2:22][CH2:23][NH2:24]>>[Br:1][C:2]1[C:3](=[O:19])[N:4]([CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[CH2:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:5]=[CH:6][C:7]=1[NH:24][CH2:23][CH2:22][N:21]([CH3:25])[CH3:20]

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 67364939HCID 67364939, compound

Product 1

HCID 53353783HCID 53353783, compound

Procedure

4-Bromo-5-(2-dimethylaminoethyl)amino-2-(3,3,5,5-tetramethylcyclohexyl)pyridazin-3-one was prepared from 4,5-Dibromo-2-(3,3,5,5-tetramethyl cyclohexyl)pyridazin-3-one in a similar manner using 2-Dimethylaminoethyl amine (4 equivalents). 1H NMR (300 MHz CDCl3) 7.51 (s, 1H), 5.53 (m, 1H), 5.33 (m, 1H), 3.34 (m, 2H), 2.60 (m, 2H), 2.3 (s, 6H), 1.55 (m, 4H), 1.3 (m, 1H), 1.15 (m, 1H), 1.15 (s, 6H), 0.95 (s, 6H).

Sources & evidence

ORD record
ord-2a70c892f0744cd49342924bcf3b9e1b
Source dataset
uspto-grants-2015_06
Patent number
US09062004B2

Reaction notes

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