O-Methylhydroxylamine hydrochloride → HCID 86707233, compound

HRID 2174674Notes

Reaction equation

HRID 2174674 reaction equation
[N:1]1[N:2]([C:10]2[N:31]=[CH:30][CH:29]=[CH:28][C:11]=2[C:12]([NH:14][CH:15]([CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:16]([OH:20])[C:17](O)=[O:18])=[O:13])[CH:3]=[C:4]2[C:9]=1[CH2:8][CH2:7][CH2:6][CH2:5]2.Cl.[CH3:33][O:34][NH2:35]>>[OH:20][CH:16]([C:17]([NH:35][O:34][CH3:33])=[O:18])[CH:15]([NH:14][C:12](=[O:13])[C:11]1[CH:28]=[CH:29][CH:30]=[N:31][C:10]=1[N:2]1[CH:3]=[C:4]2[C:9]([CH2:8][CH2:7][CH2:6][CH2:5]2)=[N:1]1)[CH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 521874O-Methylhydroxylamine hydrochlorideHCID 67958979HCID 67958979, compound

Product 1

HCID 86707233HCID 86707233, compound

Procedure

The reaction was carried out in analogy to reaction step 3.1 by reacting 3-[2-(4,5,6,7-tetrahydro-2H-indazol-2-yl)nicotinamido]-2-hydroxy-4-phenylbutanoic acid and O-methylhydroxylamine hydrochloride.

Workup

  1. customThe reaction was carried out in analogy to reaction step 3.1

Sources & evidence

ORD record
ord-0d491cbbb0984e70bc6c5b421030ec9d
Source dataset
uspto-grants-2015_06
Patent number
US09062027B2

Reaction notes

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