Hydrochloric Acid → 3-Aminooxolane-3-carboxylic acid--hydrogen chloride (1/1)

HRID 2174701Notes

Reaction equation

C(OC([NH:8][C:9]1([C:14]([OH:16])=[O:15])[CH2:13][CH2:12][O:11][CH2:10]1)=O)(C)(C)C.[ClH:17]>>[ClH:17].[NH2:8][C:9]1([C:14]([OH:16])=[O:15])[CH2:13][CH2:12][O:11][CH2:10]1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 450269433-[(tert-Butoxycarbonyl)amino]oxolane-3-carboxylic acid

Product 1

HCID 684868303-Aminooxolane-3-carboxylic acid--hydrogen chloride (1/1)

Procedure

3.5 g (15.1 mmol) 3-tert.-butoxycarbonylamino-tetrahydro-furan-3-carboxylic acid are dissolved in 150 ml of 1-molar hydrochloric acid and stirred for 1 h at room temperature. Then the reaction mixture is lyophilised.

Sources & evidence

ORD record: ord-18023cc1cbfa470b96526132ab9de553
Source dataset: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09062034B2

Reaction notes

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