HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S,6R)-3,8-Diazabicyclo[4.2.0]octan-8-yl(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)methanone → (1S,6R)-3,8-Diazabicyclo[4.2.0]octan-8-yl(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S,6R)-3,8-Diazabicyclo[4.2.0]octan-8-yl(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)methanone | HCID 67086546 | — |
| Reactant | 2-Fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 67086627 | — |
| Product | (1S,6R)-3,8-Diazabicyclo[4.2.0]octan-8-yl(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone | HCID 67086569 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Intermediate 28, substituting 5-fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid for 2-fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid. MS (ESI) mass calcd. C15H16FN5O, 301.32; m/z found 302.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062044B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-49a77b3e3d43469aabb0fb499bc57716 |
| Source note | uspto-grants-2015_06 |