Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175075Generated: November 1, 2026

Hydrochloric Acid → 4-(1-piperazinyl)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)Pyrimidine

https://huagongshe.com/reaction/2175075

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-pyrimidin-4-yl]piperazine-1-carboxylic acid tert-butyl esterHCID 67248430—
Product4-(1-piperazinyl)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)PyrimidineHCID 53250884—

Reaction Steps

The above compound is prepared analogously to FS201 starting from 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)pyrimidin-4-yl]piperazine-1-carboxylic acid tert-butyl ester. Product is the hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09062015B2
Source datasetuspto-grants-2015_06
ORD IDord-1835c933e3f44bccb49b49ed2bea5d03
Source noteuspto-grants-2015_06