Hydrochloric Acid → HCID 53250712, compound

HRID 2175077Notes

Reaction equation

HRID 2175077 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[N:18][CH:17]=[C:16]([C:20]3[CH:29]=[CH:28][C:27]4[C:26]([CH3:31])([CH3:30])[CH2:25][CH2:24][C:23]([CH3:33])([CH3:32])[C:22]=4[CH:21]=3)[N:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.Cl>>[CH3:30][C:26]1([CH3:31])[CH2:25][CH2:24][C:23]([CH3:32])([CH3:33])[C:22]2[CH:21]=[C:20]([C:16]3[N:15]=[C:14]([N:11]4[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]4)[CH:19]=[N:18][CH:17]=3)[CH:29]=[CH:28][C:27]1=2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 67248446HCID 67248446, compound

Product 1

HCID 53250712HCID 53250712, compound

Procedure

The above compound is prepared analogously to FS201 starting from 6′-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-2,3,5,6-tetrahydro-1,2′-bipyrazinyl-4-carboxylic acid tert-butyl ester. Product is the hydrochloride.

Workup

  1. customThe above compound is prepared analogously to FS201

Sources & evidence

ORD record
ord-c87b6a35ac7a41f7b0e840493ca98938
Source dataset
uspto-grants-2015_06
Patent number
US09062015B2

Reaction notes

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