Hydrochloric Acid → HCID 67607052, compound

HRID 2175081Notes

Reaction equation

HRID 2175081 reaction equation
C(OC(=O)[NH:7][CH:8]1[CH2:13][CH2:12][N:11]([C:14]2[N:19]=[C:18]([C:20]3[CH:29]=[CH:28][C:27]4[C:26]([CH3:31])([CH3:30])[CH2:25][CH2:24][C:23]([CH3:33])([CH3:32])[C:22]=4[CH:21]=3)[CH:17]=[CH:16][N:15]=2)[CH2:10][CH2:9]1)(C)(C)C.Cl>>[CH3:30][C:26]1([CH3:31])[CH2:25][CH2:24][C:23]([CH3:32])([CH3:33])[C:22]2[CH:21]=[C:20]([C:18]3[CH:17]=[CH:16][N:15]=[C:14]([N:11]4[CH2:12][CH2:13][CH:8]([NH2:7])[CH2:9][CH2:10]4)[N:19]=3)[CH:29]=[CH:28][C:27]1=2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 68380473HCID 68380473, compound

Product 1

HCID 67607052HCID 67607052, compound

Procedure

The above compound is prepared analogously to FS201 {1-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)pyrimidin-2-yl]piperidin-4-yl}carbamic acid tert-butyl ester. The product is in the form of the hydrochloride.

Sources & evidence

ORD record
ord-3eaa679d6ba14b26b9432cf90a9155df
Source dataset
uspto-grants-2015_06
Patent number
US09062015B2

Reaction notes

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