Hydrochloric Acid → HCID 53250879, compound

HRID 2175116Notes

Reaction equation

HRID 2175116 reaction equation
[CH3:1][C:2]1([CH3:23])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]3[N:16]=[C:15]([N:17]4[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]4)[CH:14]=[CH:13][CH:12]=3)[CH:9]=2)[CH2:4][CH2:3]1.[OH:24][CH2:25][CH2:26][CH2:27][CH2:28][CH:29]=O.Cl>>[CH3:1][C:2]1([CH3:23])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]3[N:16]=[C:15]([N:17]4[CH2:22][CH2:21][N:20]([CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][OH:24])[CH2:19][CH2:18]4)[CH:14]=[CH:13][CH:12]=3)[CH:9]=2)[CH2:4][CH2:3]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 202055-HydroxypentanalHCID 67249071HCID 67249071, compound

Product 1

HCID 53250879HCID 53250879, compound

Procedure

The preparation is carried out analogously to FS501 starting from 144 mg (0.47 mmol) of 1-[6-(3,3-dimethylindan-5-yl)pyridin-2-yl]piperazine and 96 mg (0.94 mmol) of 5-hydroxypentanal. The product is the hydrochloride.

Sources & evidence

ORD record
ord-9beaf10e34d0490f8a63bdf932de1aa0
Source dataset
uspto-grants-2015_06
Patent number
US09062015B2

Reaction notes

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