Hydrochloric Acid → HCID 68331456, compound

HRID 2175118Notes

Reaction equation

HRID 2175118 reaction equation
[CH3:1][C:2]1([CH3:31])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]3[N:16]=[C:15]([N:17]4[CH2:22][CH2:21][N:20]([CH2:23][CH2:24][CH2:25][CH2:26][O:27]C(=O)C)[CH2:19][CH2:18]4)[CH:14]=[CH:13][CH:12]=3)[CH:9]=2)[CH2:4][CH2:3]1.Cl>>[CH3:1][C:2]1([CH3:31])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]3[N:16]=[C:15]([N:17]4[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][CH2:25][CH2:26][OH:27])[CH2:21][CH2:22]4)[CH:14]=[CH:13][CH:12]=3)[CH:9]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 67247452HCID 67247452, compound

Product 1

HCID 68331456HCID 68331456, compound

Procedure

The preparation is carried out analogously to FS402 starting from 104 mg (0.23 mmol) of acetic acid 4-{4-[6-(3,3-dimethylindan-5-yl)pyridin-2-yl]piperazin-1-yl}butyl ester. The product is the hydrochloride.

Sources & evidence

ORD record
ord-3cf552eee1274d80a695031572c1a7a1
Source dataset
uspto-grants-2015_06
Patent number
US09062015B2

Reaction notes

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