Hydrochloric Acid → HCID 68331175, compound

HRID 2175121Notes

Reaction equation

HRID 2175121 reaction equation
[CH3:1][C:2]1([CH3:35])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([C:14]3[N:19]=[C:18]([N:20]4[CH2:25][CH2:24][CH2:23][CH:22]([NH:26][CH2:27][CH2:28][CH2:29][CH2:30][O:31]C(=O)C)[CH2:21]4)[CH:17]=[CH:16][CH:15]=3)[CH:5]=[CH:4][C:3]1=2.Cl>>[CH3:1][C:2]1([CH3:35])[CH2:11][CH2:10][C:9]([CH3:12])([CH3:13])[C:8]2[CH:7]=[C:6]([C:14]3[N:19]=[C:18]([N:20]4[CH2:25][CH2:24][CH2:23][CH:22]([NH:26][CH2:27][CH2:28][CH2:29][CH2:30][OH:31])[CH2:21]4)[CH:17]=[CH:16][CH:15]=3)[CH:5]=[CH:4][C:3]1=2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 68331458HCID 68331458, compound

Product 1

HCID 68331175HCID 68331175, compound

Procedure

The preparation is carried out analogously to FS402 starting from 49 mg (0.23 mmol) of acetic acid 4-[6′-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-3,4,5,6-tetrahydro-2H-1,2′-bipyridinyl-3-ylamino]butyl ester. The product is the hydrochloride.

Sources & evidence

ORD record
ord-6d3f779c74234edca5c670c8374229a7
Source dataset
uspto-grants-2015_06
Patent number
US09062015B2

Reaction notes

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